La melatonina es una hormona sintetizada por el organismo de forma natural a partir del triptófano y la serotonina cuya síntesis disminuye con la edad. Su liberación sigue un ritmo circadiano (aumenta con la oscuridad y disminuye con la luz). La melatonina contribuye a aliviar la sensación subjetiva de desfase horario (jet lag) y a disminuir el tiempo necesario para conciliar el sueño.
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